Täglich wächst das Wissen um die Zusammenhänge von Immunsignatur, schweren Verläufen von COVID-19 und chronischen Erkrankungen. Auf dieser Seite findest du immer die wichtigsten wissenschaftlichen Arbeiten zu dem Thema.

Hayday et al. 2020. “A Dynamic COVID-19 Immune Signature Includes Associations with Poor Prognosis.” Nature Medicine26(10):1623–35.

Hayday et al. 2020. “A Consensus Covid-19 Immune Signature Combines Immuno-Protection with Discrete Sepsis-like Traits Associated with Poor Prognosis.”

Bodenmiller et al. 2020. “A Distinct Innate Immune Signature Marks Progression from Mild to Severe COVID-19.” BioRxiv 2020.08.04.236315.

Liu et al. 2020. “A Systematic Meta-Analysis of Immune Signatures in Patients with COVID-19.” Reviews in Medical Virology n/a(n/a):e2195.

Hussell et al. 2020. “Longitudinal Immune Profiling Reveals Key Myeloid Signatures Associated with COVID-19.” Science Immunology 5(51):eabd6197.

Gnessi et al. 2020. “Visceral Fat Shows the Strongest Association with the Need of Intensive Care in Patients with COVID-19.” Metabolism 111:154319.

van den Berg, Daan F. and Anje A. te Velde. 2020. “Severe COVID-19: NLRP3 Inflammasome Dysregulated.” Frontiers in Immunology 11(June):1–6.

Saeedi-Boroujeni, A. and M. R. Mahmoudian-Sani. 2020. “COVID-19 Pandemic along with Pandemic of Lifestyle-Associated Diseases Victimizes Patients in an Inflammation Context!” Dubai Medical Journal 3(2):55–57.

Hotamisligil, Gökhan S. 2017. “Inflammation, Metaflammation and Immunometabolic Disorders.” Nature542(7640):177–85.

Luzi, Livio and Maria Grazia Radaelli. 2020. “Influenza and Obesity: Its Odd Relationship and the Lessons for COVID-19 Pandemic.” Acta Diabetologica 57(6):759–64.

Andersen, Catherine J., Kelsey E. Murphy, and Maria Luz Fernandez. 2016. “Impact of Obesity and Metabolic Syndrome on Immunity.” Advances in Nutrition 7(1):66–75.

Martineau, Adrian R. and Nita G. Forouhi. 2020. “Vitamin D for COVID-19: A Case to Answer?” The Lancet Diabetes & Endocrinology 8(9):735–36.

Marhl, Marko, Vladimir Grubelnik, Marša Magdič, and Rene Markovič. 2020. “Diabetes and Metabolic Syndrome as Risk Factors for COVID-19.” Diabetes & Metabolic Syndrome: Clinical Research & Reviews 14(4):671–77.

Brookler et al. 2020. “Relationships between Hyperinsulinaemia, Magnesium, Vitamin D, Thrombosis and COVID-19: Rationale for Clinical Management.” Open Heart 7(2):e001356.

Frasca, D. and B. B. Blomberg. 2020. “The Impact of Obesity and Metabolic Syndrome on Vaccination Success.” Pp. 86–97 in Interdisciplinary Topics in Gerontology and Geriatrics.

Gleeson, Laura E., Helen M. Roche, and Frederick J. Sheedy. 2020. “Running Title: Obesity, COVID-19 and Innate Immunometabolism.” British Journal of Nutrition 3:1–5.

Bijani, Behzad, Ali Asghar Pahlevan, Reza Qasemi-Barqi, and Hassan Jahanihashemi. 2016. “Metabolic Syndrome as an Independent Risk Factor of Hypoxaemia in Influenza a (H1N1) 2009 Pandemic.” Infezioni in Medicina24(2):123–30.

Sheridan, P. A., H. A. Paich, J. Handy, E. A. Karlsson, M. G. Hudgens, A. B. Sammon, L. A. Holland, S. Weir, T. L. Noah, and M. A. Beck. 2012. “Obesity Is Associated with Impaired Immune Response to Influenza Vaccination in Humans.” International Journal of Obesity 36(8):1072–77.

Shamshirian et al. 2020. The Role of Vitamin D in The Age of COVID-19: A Systematic Review and Meta-Analysis Along with an Ecological Approach.

Lehrer et al. 2020. “The Essential Role of Vitamin D in the Biosynthesis of Endogenous Antimicrobial Peptides May Explain Why Deficiency Increases Mortality Risk in COVID-19 Infections.” Preprints.Org (May):1–23.

Davies, Gareth, Attila R. Garami, and Joanna C. Byers. 2020. “Evidence Supports a Causal Role for Vitamin D Status in COVID-19 Outcomes.” MedRxiv 2020.05.01.20087965.

Meltzer, David O., Thomas J. Best, Hui Zhang, Tamara Vokes, Vineet Arora, and Julian Solway. 2020. “Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results.” JAMA Network Open3(9):e2019722–e2019722.

Martineau et al. 2020. “Vitamin D Supplementation to Prevent Acute Respiratory Infections: Systematic Review and Meta-Analysis of Aggregate Data from Randomised Controlled Trials.” MedRxiv 2020.07.14.20152728.

Gautier et al. 2020. “Monocytopenia, Monocyte Morphological Anomalies and Hyperinflammation Characterise Severe COVID-19 in Type 2 Diabetes.” EMBO Molecular Medicine12(10):e13038.

Hamm et al. 2020. “The Role of Visceral Adiposity in the Severity of COVID-19 : Highlights from a Unicenter Cross-Sectional Pilot Study in Germany.” (January).

Rusinek et al. 2020. “Visceral Adipose Tissue in Patients with COVID-19: Risk Stratification for Severity.” Abdominal Radiology (Mv).

Del Prato et al. 2020. “COVID-19 in People with Diabetes: Understanding the Reasons for Worse Outcomes.” The Lancet Diabetes & Endocrinology 8(9):782–92.

Zhang et al. 2020. “Association of the Insulin Resistance Marker TyG Index with the Severity and Mortality of COVID-19.” Cardiovascular Diabetology 19(1):58.

Nauck et al. 2020. “COVID-19 and Diabetes Mellitus: From Pathophysiology to Clinical Management.” Nature Reviews Endocrinology.

Finucane, Francis M. and Colin Davenport. 2020. “Coronavirus and Obesity: Could Insulin Resistance Mediate the Severity of Covid-19  Infection?” Frontiers in Public Health 8:184.


Immunstärkung durch Hormesis

Immunstärkung durch Hormesis

Die Menschen werden durchschnittlich immer älter, gleichzeitig sinkt aber der Anteil der so genannten „healthy life years“ also der in...